Psychological Development and Education ›› 2019, Vol. 35 ›› Issue (4): 495-503.doi: 10.16187/j.cnki.issn1001-4918.2019.04.13

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The Mechanism of Non-suicidal Self-injury: From the Perspective of Gene-brain-behavior Framework

WANG Quanquan, XIONG Yuke, LIU Xia   

  1. Institute of Developmental Psychology, Beijing Normal University, Beijing 100875
  • Published:2019-08-28

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Abstract: Non-suicidal self-injury (NSSI) refers to the behavior that intentionally and repeatedly harms his or her own body tissues without suicide intention. Its universality and serious consequences have aroused researchers' great attention. NSSI is the result of genetic and environmental interaction. The discussion of individual genetic traits has reached the genetic and neurological level now; the gene-brain-behavioral research paradigm provides an effective way to explore the mechanism of NSSI. In this paper, based on the existing NSSI studies and relevant research results, the polymorphism of candidate genes of NSSZ and its possible brain mechanism were comprehensively elaborated. Future research could focus on the issues of polygene-environment interaction, gene-brain-NSSZ in positive environment,the longitudinal study paradigm among adolescents, and further systematic research.

Key words: gene, brain, non-suicidal self-injury, diathesis-stress model

CLC Number: 

  • B844
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