Psychological Development and Education ›› 2025, Vol. 41 ›› Issue (4): 561-570.doi: 10.16187/j.cnki.issn1001-4918.2025.04.12

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The Effect of Parent-child Relationship on Adolescent Aggression Behavior: The Mediating Role of Mindfulness and the Moderation Role of NR3C1 Gene rs41423247 Polymorphism

HU Yiqiu1,2,3, HE Zhen1, ZENG Zihao1, LIU Shuangjin1, YANG Qin1, FANG Xiaoyi4   

  1. 1. School of Education Science, Hunan Normal University, Changsha 410081;
    2. China Research Center for Mental Health Education of Hunan Province, Changsha 410081;
    3. Cognition and Human Behavior Key Laboratory of Hunan Province4 Center for Mind-Brain Science, Hunan Normal University, Changsha 410081;
    4. Institute of Developmental Psychology, Beijing Normal University, Beijing 100875
  • Published:2025-07-12

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Abstract: Teenagers are in the critical period of life development, but also the physical and mental transition from childish to mature period. As an important part of the family environment, parent-child relationship will have an important impact on the physical and mental development of adolescents. As an important index to measure social adaptability and mental health of adolescents, adolescent aggression is closely related to parent-child relationship. Most of the previous studies explain the development mechanism of adolescent prosocial behavior from the perspective of environmental factors or only from the perspective of genetic factors. However, with the rise of gene×environment research paradigm, the formation and development of individual aggressive behavior have a new perspective. According to previous studies, parent-child relationship is an important factor affecting the development of adolescents’ aggressive behavior. In addition to parent-child relationship, mindfulness, as a positive internal trait of individuals, can also affect adolescents’ aggressive behavior. Not only that, but the development of adolescent mindfulness level is also affected by the parent-child relationship. In addition, both adolescent aggression and mindfulness are influenced by a combination of environmental and genetic factors. Therefore, the research method of gene×environment is helpful to further explain the internal development mechanism of adolescent aggressive behavior. As a consequence, environmental variables (parent-child relationship) and genetic variables (NR3C1 gene rs41423247 polymorphism) will be included in this paper to construct a moderated mediation model. To investigate whether the interaction between gene and environment affects teenagers’ aggressive behavior and mindfulness. The research object of this paper comes from a middle school in Changsha City, Hunan Province. The survey method is questionnaire. After the questionnaire survey, the students were arranged to go to the experimental area, and professionals began using oral swab to collect epithelial cells shed from students’ mouths for DNA samples Finally, 701 valid samples were obtained. This article uses SPSS 23.0 and Amos 24.0 to analyze all the data. The results show that: (1)Mindfulness plays an intermediary role in the influence of parent-child relationship on adolescent aggression; (2)The interaction between rs41423247 polymorphism and parent-child relationship significantly predicted mindfulness, and this interaction pattern corresponded to differential susceptibility model. Specifically, in the negative parent-child relationship environment, the level of mindfulness of adolescents carrying C/C genotypes is lower than that of adolescents carrying G/G and G/C genotypes. In the positive parent-child relationship environment, adolescents with C/C genotypes had higher levels of mindfulness than those with G/G and G/C genotypes.

Key words: parent-child relationship, mindfulness, adolescent aggression behavior, NR3C1 gene rs41423247 polymorphism

CLC Number: 

  • B844
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