心理发展与教育 ›› 2017, Vol. 33 ›› Issue (5): 631-640.doi: 10.16187/j.cnki.issn1001-4918.2017.05.14
• 理论与方法 • 上一篇
李何慧, 陶伍海, 彭聃龄, 丁国盛
LI Hehui, TAO Wuhai, PENG Danling, DING Guosheng
摘要: 关于阅读障碍神经机制的研究已经有很多,但到目前为止,研究者仍不完全清楚,阅读障碍者脑区的异常,究竟是阅读障碍的原因还是结果。研究者发展出不同的研究范式来探究此问题,包括学龄前研究、双对照组研究、纵向研究等。文中综述了这些研究范式各具的优势、不足和研究结果之间的一致性,并分析了确认因果关系之所以困难的原因。在此基础上,提出如下建议:(1)细致区分阅读障碍的亚类型;(2)以成熟和完善的阅读认知-神经模型为指导;(3)通过不同的研究范式进行交叉印证;(4)综合考虑脑的动态发展变化特点,和基因、环境、经验的作用等多种因素的影响。
中图分类号:
B844
Achal, S., Hoeft, F., & Bray, S.(2015). Individual Differences in Adult Reading Are Associated with Left Temporo-parietal to Dorsal Striatal Functional Connectivity. Cerebral Cortex, 26 (10), 4069-4081.Aylward, E. H., Richards, T. L., Berninger, V. W., Nagy, W. E., Field, K. M., Grimme, A. C., et al. (2003). Instructional treatment associated with changes in brain activation in children with dyslexia. Neurology, 61 (2), 212-219.Bach, S., Richardson, U., Brandeis, D., Martin, E., & Brem, S. (2013). Print-specific multimodal brain activation in kindergarten improves prediction of reading skills in second grade. NeuroImage, 82, 605-615.Bellander, M., Berggren, R., Mårtensson, J., Brehmer, Y., Wenger, E., Li, T.-Q., et al. (2016). Behavioral correlates of changes in hippocampal gray matter structure during acquisition of foreign vocabulary. NeuroImage, 131, 205-213.Black, J. M., Tanaka, H., Stanley, L., Nagamine, M., Zakerani, N., Thurston, A., et al. (2012). Maternal history of reading difficulty is associated with reduced language-related gray matter in beginning readers. NeuroImage, 59 (3), 3021-3032.Boets, B., de Beeck, H. P. O., Vandermosten, M., Scott, S. K., Gillebert, C. R., Mantini, D., et al. (2013). Intact but less accessible phonetic representations in adults with dyslexia. Science, 342 (6163), 1251-1254.Cao, F., Bitan, T., & Booth, J. R. (2008). Effective brain connectivity in children with reading difficulties during phonological processing. Brain and Language, 107 (2), 91-101.Cao, F., Yan, X., Wang, Z., Liu, Y., Wang, J., Spray, G. J., et al. (2016). Neural signatures of phonological deficits in Chinese developmental dyslexia. NeuroImage, 146, 301-311.Cao, F., Yan, X., Wang, Z., Liu, Y., Wang, J., Spray, G. J., et al. (2017). Neural signatures of phonological deficits in Chinese developmental dyslexia. NeuroImage, 146, 301-311.Carreiras, M., Seghier, M. L., Baquero, S., Estévez, A., Lozano, A., Devlin, J. T., et al. (2009). An anatomical signature for literacy. Nature, 461 (7266), 983-986.Castles, A., & Coltheart, M. (2004). Is there a causal link from phonological awareness to success in learning to read? Cognition, 91 (1), 77-111.Clark, K. A., Helland, T., Specht, K., Narr, K. L., Manis, F. R., Toga, A. W., et al. (2014). Neuroanatomical precursors of dyslexia identified from pre-reading through to age 11. Brain, 137 (12), 3136-3141.Costanzo, F., Menghini, D., Caltagirone, C., Oliveri, M., & Vicari, S. (2013). How to improve reading skills in dyslexics:the effect of high frequency rTMS. Neuropsychologia, 51 (14), 2953-2959.Davis, N., Barquero, L., Compton, D. L., Fuchs, L. S., Fuchs, D., Gore, J. C., et al. (2011). Functional correlates of children's responsiveness to intervention. Developmental Neuropsychology, 36 (3), 288-301.Eden, G. F., Jones, K. M., Cappell, K., Gareau, L., Wood, F. B., Zeffiro, T. A., et al. (2004). Neural changes following remediation in adult developmental dyslexia. Neuron, 44 (3), 411-422.Eicher, J. D., Montgomery, A. M., Akshoomoff, N., Amaral, D. G., Bloss, C. S., Libiger, O., et al. (2016). Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children. Brain Imaging and Behavior, 10 (1), 272-282.Elbro, C., Nielsen, I., & Petersen, D. K. (1994). Dyslexia in adults:Evidence for deficits in non-word reading and in the phonological representation of lexical items. Annals of Dyslexia, 44 (1), 203-226.Evans, T. M., Flowers, D. L., Napoliello, E. M., & Eden, G. F. (2014). Sex-specific gray matter volume differences in females with developmental dyslexia. Brain Structure and Function, 219 (3), 1041-1054.Finn, E. S., Shen, X., Holahan, J. M., Scheinost, D., Lacadie, C., Papademetris, X., et al. (2014). Disruption of functional networks in dyslexia:a whole-brain, data-driven analysis of connectivity. Biological Psychiatry, 76 (5), 397-404.Frye, R. E., Liederman, J., Malmberg, B., McLean, J., Strickland, D., & Beauchamp, M. S. (2010). Surface area accounts for the relation of gray matter volume to reading-related skills and history of dyslexia. Cerebral Cortex, 20, 2625-2635.Hoeft, F., Hernandez, A., McMillon, G., Taylor-Hill, H., Martindale, J. L., Meyler, A., et al. (2006). Neural basis of dyslexia:a comparison between dyslexic and nondyslexic children equated for reading ability. The Journal of Neuroscience, 26 (42), 10700-10708.Hoeft, F., McCandliss, B. D., Black, J. M., Gantman, A., Zakerani, N., Hulme, C., et al. (2011). Neural systems predicting long-term outcome in dyslexia. Proceedings of the National Academy of Sciences, 108 (1), 361-366.Hoeft, F., Meyler, A., Hernandez, A., Juel, C., Taylor-Hill, H., Martindale, J. L., et al. (2007). Functional and morphometric brain dissociation between dyslexia and reading ability. Proceedings of the National Academy of Sciences, 104 (10), 4234-4239.Hosseini, S. H., Black, J. M., Soriano, T., Bugescu, N., Martinez, R., Raman, M. M., et al. (2013). Topological properties of large-scale structural brain networks in children with familial risk for reading difficulties. NeuroImage, 71, 260-274.Im, K., Raschle, N. M., Smith, S. A., Grant, P. E., & Gaab, N. (2015). Atypical Sulcal Pattern in Children with Developmental Dyslexia and At-Risk Kindergarteners. Cerebral Cortex, 26, 1138-1148.Jednoróg, K., Gawron, N., Marchewka, A., Heim, S., & Grabowska, A. (2014). Cognitive subtypes of dyslexia are characterized by distinct patterns of grey matter volume. Brain Structure and Function, 219 (5), 1697-1707.Kovelman, I., Norton, E. S., Christodoulou, J. A., Gaab, N., Lieberman, D. A., Triantafyllou, C., et al. (2012). Brain basis of phonological awareness for spoken language in children and its disruption in dyslexia. Cerebral Cortex, 22 (4), 754-764.Koyama, M. S., Di Martino, A., Kelly, C., Jutagir, D. R., Sunshine, J., Schwartz, S. J., et al. (2013). Cortical signatures of dyslexia and remediation:an intrinsic functional connectivity approach. PloS One, 8 (2), e55454.Krafnick, A. J., Flowers, D. L., Luetje, M. M., Napoliello, E. M., & Eden, G. F. (2014). An Investigation into the Origin of Anatomical Differences in Dyslexia. The Journal of Neuroscience, 34 (3), 901-908.Krafnick, A. J., Flowers, D. L., Napoliello, E. M., & Eden, G. F. (2011). Gray matter volume changes following reading intervention in dyslexic children. NeuroImage, 57 (3), 733-741.Kraft, I., Cafiero, R., Schaadt, G., Brauer, J., Neef, N. E., Müller, B., et al. (2015). Cortical differences in preliterate children at familiar risk of dyslexia are similar to those observed in dyslexic readers. Brain, 138 (9), e378-e378.Langer, N., Peysakhovich, B., Zuk, J., Drottar, M., Sliva, D. D., Smith, S., et al. (2017). White matter alterations in infants at risk for developmental dyslexia. Cerebral Cortex, 27 (2), 1027-1036.Linkersdörfer, J., Lonnemann, J., Lindberg, S., Hasselhorn, M., & Fiebach, C. J. (2012). Grey matter alterations co-localize with functional abnormalities in developmental dyslexia:an ALE meta-analysis. PloS One, 7 (8), e43122.Liu, K., Shi, L., Chen, F., Waye, M. M., Lim, C. K., Cheng, P.-w., et al. (2015). Altered topological organization of brain structural network in Chinese children with developmental dyslexia. Neuroscience Letters, 589, 169-175.Lyon, G. R., Shaywitz, S. E., & Shaywitz, B. A. (2003). A definition of dyslexia. Annals of Dyslexia, 53 (1), 1-14.Ma, Y., Koyama, M. S., Milham, M. P., Castellanos, F. X., Quinn, B. T., Pardoe, H., et al. (2015). Cortical thickness abnormalities associated with dyslexia, independent of remediation status. NeuroImage:Clinical, 7, 177-186.Maisog, J. M., Einbinder, E. R., Flowers, D. L., Turkeltaub, P. E., & Eden, G. F. (2008). A Meta-analysis of Functional Neuroimaging Studies of Dyslexia. Annals of the New York Academy of Sciences, 1145 (1), 237-259.Mascheretti, S., De Luca, A., Trezzi, V., Peruzzo, D., Nordio, A., Marino, C., et al. (2017). Neurogenetics of developmental dyslexia:from genes to behavior through brain neuroimaging and cognitive and sensorial mechanisms. Translational Psychiatry, 7 (1), e987.Morken, F., Helland, T., Hugdahl, K., & Specht, K. (2016). Reading in dyslexia across literacy development:A longitudinal study of effective connectivity. NeuroImage, 144, 92-100.Myers, C. A., Vandermosten, M., Farris, E. A., Hancock, R., Gimenez, P., Black, J. M., et al. (2014). White matter morphometric changes uniquely predict children's reading acquisition. Psychological Science, 25 (10), 1870-1883.Odegard, T. N., Ring, J., Smith, S., Biggan, J., & Black, J. (2008). Differentiating the neural response to intervention in children with developmental dyslexia. Annals of Dyslexia, 58 (1), 1-14.Olulade, O. A., Napoliello, E. M., & Eden, G. F. (2013). Abnormal visual motion processing is not a cause of dyslexia. Neuron, 79 (1), 180-190.Ozernov-Palchik, O., & Gaab, N. (2016). Tackling the Early Identification of Dyslexia with the Help of Neuroimaging. Perspectives on Language and Literacy, 42 (1), 11-17.Powers, S. J., Wang, Y., Beach, S. D., Sideridis, G. D., & Gaab, N. (2016). Examining the relationship between home literacy environment and neural correlates of phonological processing in beginning readers with and without a familial risk for dyslexia:an fMRI study. Annals of Dyslexia, 66 (3), 337-360.Qi, T., Gu, B., Ding, G., Gong, G., Lu, C., Peng, D., et al. (2016). More bilateral, more anterior:Alterations of brain organization in the large-scale structural network in Chinese dyslexia. NeuroImage, 124, 63-74.Raschle, N. M., Becker, B. L. C., Smith, S., Fehlbaum, L. V., Wang, Y., & Gaab, N. (2015). Investigating the influences of language delay and/or familial risk for dyslexia on brain structure in 5-year-olds. Cerebral Cortex, 27 (1), 764-776.Raschle, N. M., Chang, M., & Gaab, N. (2011). Structural brain alterations associated with dyslexia predate reading onset. NeuroImage, 57 (3), 742-749.Raschle, N. M., Zuk, J., & Gaab, N. (2012). Functional characteristics of developmental dyslexia in left-hemispheric posterior brain regions predate reading onset. Proceedings of the National Academy of Sciences, 109 (6), 2156-2161.Richards, T. L., & Berninger, V. W. (2008). Abnormal fMRI connectivity in children with dyslexia during a phoneme task:Before but not after treatment. Journal of Neurolinguistics, 21 (4), 294-304.Richlan, F. (2012). Developmental dyslexia:dysfunction of a left hemisphere reading network. Frontiers in Human Neuroscience, 6, 120.Richlan, F., Kronbichler, M., & Wimmer, H. (2009). Functional abnormalities in the dyslexic brain:A quantitative meta-analysis of neuroimaging studies. Human Brain Mapping, 30 (10), 3299-3308.Richlan, F., Kronbichler, M., & Wimmer, H. (2011). Meta-analyzing brain dysfunctions in dyslexic children and adults. NeuroImage, 56 (3), 1735-1742.Richlan, F., Kronbichler, M., & Wimmer, H. (2013). Structural abnormalities in the dyslexic brain:A meta-analysis of voxel-based morphometry studies. Human Brain Mapping, 34 (11), 3055-3065.Saygin, Z. M., Norton, E. S., Osher, D. E., Beach, S. D., Cyr, A. B., Ozernov-Palchik, O., et al. (2013). Tracking the roots of reading ability:white matter volume and integrity correlate with phonological awareness in prereading and early-reading kindergarten children. The Journal of Neuroscience, 33 (33), 13251-13258.Scerri, T. S., & Schulte-Körne, G. (2010). Genetics of developmental dyslexia. European Child & Adolescent Psychiatry, 19 (3), 179-197.Schlaggar, B. L., & McCandliss, B. D. (2007). Development of neural systems for reading. Annu. Rev. Neurosci., 30, 475-503.Schurz, M., Wimmer, H., Richlan, F., Ludersdorfer, P., Klackl, J., & Kronbichler, M. (2015). Resting-state and task-based functional brain connectivity in developmental dyslexia. Cerebral Cortex, 25 (10), 3502-3514.Shaywitz, B. A., Shaywitz, S. E., Pugh, K. R., Mencl, W. E., Fulbright, R. K., Skudlarski, P., et al. (2002). Disruption of posterior brain systems for reading in children with developmental dyslexia. Biological Psychiatry, 52 (2), 101-110.Shaywitz, S. E., & Shaywitz, B. A. (2005). Dyslexia (specific reading disability). Biological Psychiatry, 57 (11), 1301-1309.Simos, P. G., Fletcher, J. M., Bergman, E., Breier, J., Foorman, B., Castillo, E., et al. (2002). Dyslexia-specific brain activation profile becomes normal following successful remedial training. Neurology, 58 (8), 1203-1213.Skeide, M. A., Kraft, I., Müller, B., Schaadt, G., Neef, N. E., Brauer, J., et al. (2016). NRSN1 associated grey matter volume of the visual word form area reveals dyslexia before school. Brain, 139 (10), 2792-2803.Specht, K., Hugdahl, K., Ofte, S., NYGÅRD, M., BJØRNERUD, A., Plante, E., et al. (2009). Brain activation on pre-reading tasks reveals at-risk status for dyslexia in 6-year-old children. Scandinavian Journal of Psychology, 50 (1), 79-91.Thiebaut de Schotten, M., Cohen, L., Amemiya, E., Braga, L. W., & Dehaene, S. (2012). Learning to read improves the structure of the arcuate fasciculus. Cerebral Cortex, 24 (4), 989-995.Vandermosten, M., Boets, B., Poelmans, H., Sunaert, S., Wouters, J., & Ghesquière, P. (2012). A tractography study in dyslexia:neuroanatomic correlates of orthographic, phonological and speech processing. Brain, 135 (3), 935-948.Vandermosten, M., Boets, B., Wouters, J., & Ghesquière, P. (2012). A qualitative and quantitative review of diffusion tensor imaging studies in reading and dyslexia. Neuroscience & Biobehavioral Reviews, 36 (6), 1532-1552.Vandermosten, M., Hoeft, F., & Norton, E. S. (2016). Integrating MRI brain imaging studies of pre-reading children with current theories of developmental dyslexia:a review and quantitative meta-analysis. Current Opinion in Behavioral Sciences, 10, 155-161.Vandermosten, M., Vanderauwera, J., Theys, C., De Vos, A., Vanvooren, S., Sunaert, S., et al. (2015). A DTI tractography study in pre-readers at risk for dyslexia. Developmental Cognitive Neuroscience, 14, 8-15.Wang, Y., Mauer, M. V., Raney, T., Peysakhovich, B., Becker, B. L., Sliva, D. D., et al. (2016). Development of Tract-Specific White Matter Pathways During Early Reading Development in At-Risk Children and Typical Controls. Cerebral Cortex, 27 (4), 2469-2485.Xia, Z., Hoeft, F., Zhang, L., & Shu, H. (2016). Neuroanatomical anomalies of dyslexia:Disambiguating the effects of disorder, performance, and maturation. Neuropsychologia, 81, 68-78.Yamada, Y., Stevens, C., Dow, M., Harn, B. A., Chard, D. J., & Neville, H. J. (2011). Emergence of the neural network for reading in five-year-old beginning readers of different levels of pre-literacy abilities:An fMRI study. NeuroImage, 57 (3), 704-713.Yeatman, J. D., Dougherty, R. F., Ben-Shachar, M., & Wandell, B. A. (2012). Development of white matter and reading skills. Proceedings of the National Academy of Sciences, 109 (44), E3045-E3053.冯小霞, 李乐, 丁国盛. (2016). 发展性阅读障碍的脑区连接异常. 心理科学进展, 24 (12), 1864-1872.孟泽龙, 张逸玮, 毕鸿燕. (2017). 发展性阅读障碍亚类型研究进展. 心理发展与教育, 33 (1), 113-121.杨远滨, 肖娜, 李梦瑶, 宋为群. (2011). 经颅磁刺激与经颅直流电刺激的比较. 中国康复理论与实践, 17 (12), 1131-1135. |
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